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Retatrutide
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Retatrutide

Retatrutide, also known as LY3437943, is a glucagon-like peptide 1 agonist; what separates this peptide from the others is it also targets gastric inhibitory polypeptide receptor (GIPR) and glucagon receptors (GCGR), making it a triagonist.

In the lab settings, Retatrutide mimics the natural glucagon and glucose production within the hepatocytes, while inducing lipolysis in the adipocytes.

CAD $130.00 – CAD $250.00

5mg
10mg
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5mg, 10mg

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Retatrutide

CAD $130.00 – CAD $250.00
Retatrutide, also known as LY3437943, is a glucagon-like peptide 1 agonist; what separates this peptide from the others is it also targets gastric inhibitory polypeptide receptor (GIPR) and glucagon receptors (GCGR), making it a triagonist. In the lab settings, Retatrutide mimics the natural glucagon and glucose production within the hepatocytes, while inducing lipolysis in the adipocytes.
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Tesamorelin

CAD $70.00 – CAD $125.00
Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analog. It was based on the 44 amino acids sequence of GHRH and contains a trans-3 hexenoic group to protect it from enzymatic degradation. These modifications allow it to be more stable and have a longer half-life.   Just like Sermorelin, Ipamorelin or GHRP-2, Tesamorelin is considered a growth hormone secretagogue (GHS) which stimulates the secretion of GH and increases the level of insulin-like growth factor (IGF-1). The importance of IGF-1 is it tends to be lower in patients with obesity, diabetes and especially in those with lipodystrophy. References: 
  1. Sinha DK, Balasubramanian A, Tatem AJ, Rivera-Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Transl Androl Urol. 2020 Mar;9(Suppl 2):S149-S159. doi: 10.21037/tau.2019.11.30. PMID: 32257855; PMCID: PMC7108996.
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Oxytocin 10mg

CAD $67.00
Oxytocin is a naturally occurring, cyclic nonapeptide which acts as a neurotransmitter in the brain. This naturally occurring peptide is vital in many functions concerning reproduction and birth, it’s the principal uterine-contracting and milk-ejecting hormone.   An interesting thing about Oxytocin is that it’s one of the few hormones that exhibit a positive feedback loop; in other words, the release of oxytocin kicks certain actions in motions, which promote even more oxytocin release. References:
  1. https://www.bjanaesthesia.org/article/S0007-0912(17)33682-6/pdf
  2. https://www.sciencedirect.com/science/article/pii/S2667174324001083
  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC5404956/
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Semaglutide

CAD $105.00 – CAD $190.00
This is a synthetic peptide modeled after the naturally occurring hormone glucagon-like peptide-1 (GLP-1). GLP-1 is an incretin, a gut-derived peptide secreted in response to a meal, that regulates insulin secretion based on glucose levels in the blood. This GLP-1 agonist was developed specifically to have an extended half-life without losing potency. Since it falls under the category of glucagon-like peptide-1 receptor agonists, it acts to prompt the body to secrete more insulin and inhibit glucagon secretion. By allowing the body to secrete more insulin and inhibiting the secretion of glucagon, this joint effort brings blood glucose levels down.
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AOD9604

CAD $50.00 – CAD $90.00
AOD9604 is a derivative of human growth hormone (hGH) and a modified version of the hGH fragment 176-191 peptide, incorporating a di-sulfide bridge. What’s exciting about this peptide is that it does not affect IGF-1 or insulin levels and is, therefore, not a risk in promoting glucose intolerance.
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Sermorelin 10mg

CAD $120.60
Sermorelin is a 29 amino acid human growth hormone-releasing hormone (GHRH) analogue and it’s actually the shortest synthetic peptide with full GHRH biological activity. It’s considered a growth hormone secretagogue (GHS) which was initially developed only to test the secretion of GH.   What sermorelin essentially does is it mimics the hypothalamic peptide GHRH and acts directly on the pituitary gland stimulating the production of GH. It also increases the proliferation of somatotroph cells’ ability to secrete HGH. Source:
  1. Walker RF. Sermorelin: a better approach to management of adult-onset growth hormone insufficiency? Clin Interv Aging. 2006;1(4):307-8. doi: 10.2147/ciia.2006.1.4.307. PMID: 18046908; PMCID: PMC2699646.
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BPC 157 10mg

CAD $134.00
Body protection compound 157, or BPC-157, is an overall body protection compound fragment that’s 15 amino acids long, falling under the pentadecapeptide category. BPC-257 is derived from the gastric juice and, as such, is much more stable and, above all, resilient to the destructive enzymes commonly found in the gastric juice.   Research around BPC-157 showed its incredible cytoprotective properties, as it provides cell protection against gastric mucosal injury. Researchers believe this peptide plays an important role in the brain-gut axis and enables this communication between our central nervous and endocrine systems.     References:
  1. BPC-157 also interacts with dopamine, glutamate but it also helps with the upregulation of growth factors and may affect growth hormone secretion.
  2. Gwyer D, Wragg NM, Wilson SL. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell Tissue Res. 2019 Aug;377(2):153-159. doi: 10.1007/s00441-019-03016-8. Epub 2019 Mar 27. PMID: 30915550.
  3. Chang CH, Tsai WC, Hsu YH, Pang JH. Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts. Molecules. 2014 Nov 19;19(11):19066-77. doi: 10.3390/molecules191119066. PMID: 25415472; PMCID: PMC6271067.
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